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diagnosis management differential rash oncology syndrome antibiotics hemeonc hemophagocytic hlh infant lp lymphohistiocytosis pediatrics peds petechiae petechial stepbystep stratification sweet
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
or absence of fever ... If fever is present ... but without a fever ... #Diagnosis #Dermatology ... #Nikolsky #Febrile
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH Vesiculobullous rashes provoke significant angst in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... these rashes as febrile ... vesiculobullous rash and a fever ... localized lesions and fever ... #Diagnosis #Dermatology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... components of the algorithm ... an infant with fever ... Pediatrics #Peds #Febrile ... Stratification #Fever
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... High-risk Features ... instability - New-onset fever ... #Diagnosis #Dermatology ... Color #Targetoid #Algorithm
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Syndrome (Acute Febrile ... Fever, temperature ... Excellent response to treatment ... Criteria #Diagnosis #Hematology ... #Dermatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... : No • Treatment ... Transfusion #Reactions #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Red Flags: • Fever ... medication Febrile ... Differential #Diagnosis #Algorithm ... #Causes #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
acute or subacute febrile ... following: • Fever ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Purpuric Rashes- THE ALGORITHMIC ... petechiae/purpura with fever ... petechiae/purpura with fever ... the patient is afebrile ... #Diagnosis #Dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... diagnosis #management #hematology
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