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diagnosis hematology activetb causes differential hemophagocytic latenttb lymphohistiocytosis rheumatology tb tuberculosis anesthesia anesthesiology brain checklist classification crypto cryptococcal hodgkins hyperthermia
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... following: • Fever ... Lymphohistiocytosis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... syndromes Clinical ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... Actively maintained fever ... amphetamines) Toxic: • Radiologic ... Checklist #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Dermatomyositis Clinical ... Muscle swelling - Fever ... ) • AKI: BUN/Cr ... Differential #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • Dyspnea • Fever ... Hodgkin Lymphoma Treatment ... cycles without XR ... hematology #oncology #management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Active TB: • Fever ... and Culture • CXR ... disease • Check CXR ... TB #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Active TB: • Fever ... and Culture • CXR ... disease • Check CXR ... TB #Diagnosis #Management
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Headache x1 mo, +neck ... are common but fever ... half. absence of fever ... Standard treatment ... #radiology
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