31 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... #Diagnosis #Management
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... #Diagnosis #Management ... #Pediatrics #Peds ... Stratification #Fever
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... Presentation: • Fever ... Diagnostic Criteria - Fever ... #rheumatology #pediatrics ... #treatment
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
treat infectious diseases ... Pneumonia - Typhoid fever ... respiratory distress syndrome ... #Pharmacology #Management ... #Treatment #Indications
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
: • 80% have fever ... Blood cultures • CXR ... ) • CXR upright ... decubitus - air fluid level ... Intervention: - Fevers
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... organ damage • Treatment ... acid, Elevated Cr ... TLS #diagnosis #management
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... active ROM +/- fever ... necrosis, Lyme disease ... 90% sensitive in pediatrics ... cervical, anal Cxs
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Insufficiency, Liver ... , Severe Valve Disease ... Abdominal compartment syndrome ... #criticalcare #algorithm ... #treatment #management
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... old on day ≥7 of fever ... echo is positive, treatment ... within 10 d of fever ... Diagnosis #Peds #Pediatrics
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... APML #diagnosis #management