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diagnosis hematology causes hemolytic macrocytic classification elevatedmcv gap globulin hemolysis hodgkins leukemia lymphoma macrocytosis management mds myelodysplasia myelodysplastic plasmacytoma polycythemia
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Increased red cell ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypothyroid • Liver ... #Macrocytic #Anemia ... #differential # ... diagnosis #algorithm ... #hematology #workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... • Sickle cells ... #workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Macrocytosis, Target Cells ... #Diagnosis #Algorithm ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... , weight loss, abdominal ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Diagnosis Algorithm ... Too many cells in ... Better call hematology ... #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
bone marrow at a level ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... myeloma • Plasma cell ... Sarcoidosis) • Liver ... anemia • Other ... Gap #ProteinGap #differential
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