16 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... level of expression ... #Cholestatic #Transaminitis ... #differential #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... • NAFLD • Cirrhosis ... Function #Tests #LFTs ... Differential #Diagnosis #hepatology ... #transaminitis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... Biliary tree or bile flow ... #FunctionTest #LFTs ... #Elevation #Transaminitis ... #diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
and Bleeding in Liver ... • Decr TFPI Low ... Bleeding #Clot #Cirrhosis ... #Pathophysiology ... #Hepatology #Liver
Demonstrating Rostral Venous Flow of Caput Medusae in Portal Hypertension

We do the milking method as depicted
Rostral Venous Flow ... In this case the ... #Hypertension #PhysicalExam ... direction #veins #cirrhosis ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Hepatocellular Level ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology ... #transaminitis
Dilated Abdominal Veins and Caput Medusae - Direction of Blood Flow

Vein Milking technique can be used
Direction of Blood Flow ... determine the cause ... #physicalexam # ... diagnosis #hepatology ... #cirrhosis #obstruction