31 results
Flapping tremors of Asterixis

DDx
- Decompensated cirrhosis or acute liver failure.
- Renal failure /azotemia.
- Respiratory failure with
Flapping tremors of Asterixis ... Decompensated cirrhosis ... or acute liver ... hyperammonemia #PhysicalExam ... clinical #diagnosis #video
Cirrhosis leading to Chronic Liver Failure - Clinical Signs and Symptoms

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings
Cirrhosis leading ... to Chronic Liver ... and Symptoms #Cirrhosis ... Signs #Symptoms #PhysicalExam ... Findings #Diagnosis #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... #Chronic #Liver ... #Hepatology #gastroenterology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... • NAFLD • Cirrhosis ... • Chronic Viral ... Hepatopathy • Acute ... (Drug-induced liver
Asterixis on Physical Exam

Asterixis, aka liver flap, indicates at least Grade 2 hepatic encephalopathy in a
, aka liver flap ... a patient with cirrhosis ... #PhysicalExam # ... clinical #video ... #cirrhosis #flap
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... Nonalcoholic fatty liver ... heart failure (chronic ... #Differential #Hepatology ... #Cirrhosis #Causes
Asterixis is a type of negative myoclonus characterized by irregular lapses of posture of various body
Asterixis is a type ... characterized by irregular lapses ... associated with liver ... hyperammonemia #PhysicalExam ... clinical #diagnosis #video
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
to non-cirrhotic ... /acute hepatitis ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... injury: > 3 • Chronic ... #differential #Hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... 5-10x normal - Chronic ... #Patterns #Liver