17 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint ... Inhibitor Toxicity ... Complications and Treatment ... #SideEffects #Table ... #Diagnosis #Pharmacology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Drugs Used for the ... clinical trial Ever ... smfarmhosp_smfh #Drugs ... #COVID19 #Pharmacology ... #Table #Management
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
Know" series - Drug ... vary depending on treatment ... mortality at a higher level ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Neuroleptic malignant syndrome ... Extreme rigidity, fever ... tremor ("rabbit syndrome ... months or years of treatment ... #SideEffects #pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... - Cytotoxic drugs ... HCV - HIV • Immune ... index < 2 • EPO Level ... aplastic anemia Treatment
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug ... Level Monitoring ... at anytime if toxicity ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... Inflammatory Syndrome ... decrease in HIV-1 RNA level ... reaction/ART toxicity ... #Inflammatory #Syndrome
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... antipsychotic drugs ... metabolized in the liver ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
abnormality, Medication/Drug ... toxicity, Metabolic ... elevated protein level ... persistent altered level ... epilepticus Treatment