21 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Coronary arteries - Fever ... : • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... rheumatoid factor level ... C4 complement level ... classification #rheumatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... and hepatorenal syndrome ... • Budd Chiari syndrome ... • Infiltrative diseases ... Veno-occlusive disease
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... treat infectious diseases ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Pharmacology #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... Mucocutaneous lymph node syndrome ... • Behcet syndrome ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Episcleritis Signs ... , breast CA - Hematologic ... Leukocytoclastic vasculitis ... #diagnosis #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
syndromes Clinical ... is the main clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Liver diseases ... Low serum IgG level ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology