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diagnosis hematology blood product reactions activation antimda5 antimda5dm dermatology dermatomyositis fhc fitzhughcurtis hemophagocytic lymphohistiocytosis macrophage mas syndrome transfusion transfusions treatment
Case of Fitz-Hugh-Curtis (FHC) Adhesions 28F +4d RUQ pain worse w/ inspiration, 102F fever, no vaginal discharge,
inspiration, 102F fever ... vaginal discharge, rash ... enhancement of liver ... FitzHughCurtis #FHC #Clinical ... #Photo
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... signs and symptoms ... following: • Fever ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Petechial or purpuric rash ... thrombocytopenia • Liver
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... Dermatomyositis • Fever ... disease and ILD • Liver ... Liver biopsies show ... Dermatomyositis #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... maculopapular rash ... Sx include: fever ... eruptions, diarrhea, liver
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... have drop in Hct, fever ... maculopapular rash ... Sx include: fever ... eruptions, diarrhea, liver
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