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diagnosis hematology activation antimda5dm dermatology dermatomyositis hemophagocytic hlh lymphohistiocytosis macrophage mas syndrome treatment
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... Dermatomyositis • Fever ... disease and ILD • Liver ... Liver biopsies show ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... thrombocytopenia • Liver ... ALT ↑ bilirubin level
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Diagnosis: HLH signs ... following: • Fever ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management
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