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injury kidney management nephrology differential classification hepatology rheumatology syndrome ain apml autoimmune cancer causes dermatology differentiation dili druginduced drugs erythematosus
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
When to suspect AIN ... sensitive) • AKI ... associated with AIN ... Interstitial #Nephritis #AIN ... #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework ... Pigment, Protein) • AIN ... nephrology #causes #algorithm
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
change disease • Hematologic ... malignancies Treatment ... Methotrexate • AIN ... #Cancer #Oncology ... #Differential #Diagnosis
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... (AKI) Prerenal: ... , tenofovir • AIN ... #Drugs #pharmacology ... #differential #diagnosis
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
cardiorenal syndrome) • Liver ... prolonged prerenal AKI ... nephritis (AIN) ... tract infection • Medications ... Classification #diagnosis
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... • AIN → Consider ... #Acute #Kidney
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... duration), Several medications ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Algorithm #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... , AIH diagnosis ... Management - Strong indications ... regarding need for treatment ... #Hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... effusions, weight gain ... #management #hematology ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Inflammation and pain ... , breast CA - Hematologic ... Treatment: - Systemic ... #dermatology #oncology
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