54 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... #LiverInjury #Hepatology ... #Pharmacology # ... Causes #DILI
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Diagnosis Algorithm DILI ... non-essential drug/HDS treatments ... for alternative causes ... Diagnosis #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... disease, liver ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Trauma: Shock liver ... • Iatrogenic: DILI ... Differential #Diagnosis #causes ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... , vomiting, abdominal ... 10x ULN), ↑Tbili/Dbili ... Antithrombin Ill • Ultrasound ... #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... • Iatrogenic: DILI ... Unconjugated Bili ... > 90% of Total Bili ... diagnosis #algorithm #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... to cirrhosis, Abdominal ... Cirrhosis, Polycystic liver ... differential #diagnosis #causes ... #hepatology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
gas on hepatic ultrasound ... ileus), intra-abdominal ... variety of other causes ... portal #venousgas #ultrasound ... #hepatology #liver
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... : Urine Common Uses ... vomiting, diarrhea & abdominal ... #Indications #Pharmacology ... #hematology
Liver Abscess
•	Pyogenic abscess, accounts for 80% of abscess.
•	Amebic abscess due to Entamoeba histolytica, accounts for 10%.
•	Fungal
the bacterial cases ... an occult intra‐abdominal ... & abdominal pain ... abscess & antibiotic treatment ... cornerstones of treatment