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management differential hematology liver rheumatology algorithm gastroenterology aflp causes cirrhosis hemophagocytic hepatopulmonary hlh jugular lemierres lymphohistiocytosis neck obstetrics pocus pregnancy
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... Brain Failure Lung ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
- Differential Diagnosis ... CA, small cell lung ... Trauma: Shock liver ... • Autoimmune hepatitis ... #causes #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... CA, small cell lung ... • Gilbert's syndrome ... #algorithm #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... Clinical Presentation ... Highly variable clinical ... regarding need for treatment ... #Management #Hepatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
syndromes Clinical ... is the main clinical ... rash) • Heart, lung ... Treatment: • Corticosteroids ... #Diagnosis #Management
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... : Viral Hepatitis ... Maternal Support - Critical ... #Pregnancy #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #differential #diagnosis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... and hepatorenal syndrome ... Cirrhosis/acute hepatitis ... #causes #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... diseases and hepatitis ... Low serum IgG level ... : • Nephrotic syndrome
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... shunt (Type 2) Clinical ... on radioactive lung ... #treatment #hepatology
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