41 results
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... if neutropenic fever ... #management #treatment ... #hematology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... Insufficiency, Liver ... #Differential #Diagnosis ... #criticalcare # ... algorithm #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, difficult to diagnose ... malignant) to diagnose ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... /full triad at diagnosis ... after 2 years of treatment ... Autoimmune #Myositis #diagnosis ... #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... widely used for diagnosis ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Hyperacute Hypoxemia - Workup and Management
Differential Diagnosis: Aspiration, Flash Pulmonary Edema, Mucous Plugging, Bronchospasm, Pulmonary Embolism,
Differential Diagnosis ... edema), Lung Exam, POCUS ... lung sliding) Diagnostics ... #Management #treatment ... #criticalcare
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Differential Diaqnoses ... Stills #Disease #diagnosis ... #management #treatment ... #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... infections Diagnostic ... Criteria - Fever ... KD #vasculitis #rheumatology ... #management #treatment