23 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Injury (DILI) ... #Acute #Chronic ... #Cirrhosis #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... ALF): • Liver ... injury < 26 weeks ... • Gilbert's syndrome ... #differential #Hepatology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
ascites removed • Acute ... kidney injury ( ... • Hepatorenal syndrome ... #Cirrhosis #treatment ... #hepatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Muscle swelling - Fever ... per day until stable ... Differential #Diagnosis #Management ... #nephrology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Insufficiency, Liver ... Medications, Spinal Cord Injury ... • Obstructive: Pulmonary ... Abdominal compartment syndrome ... #management
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
immunosuppression • Acute ... injury (INR > 2 ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : • Common: fever ... Imaging: CXR- pulmonary ... APML #diagnosis #management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... At least 3 of (Acute ... , and CXR with pulmonary ... : No • Treatment ... diagnosis #comparison #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... pulmonary edema ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Medications #Table
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
days after an acute ... injury or after ... including DM • Treatment ... of spinal cord injury ... #treatment