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oncology algorithm disorders eosinophil eosinophilia erythematosus gap globulin hodgkins infections infectiousdiseases leukemia lupus management mds mycobacteria myelodysplasia myelodysplastic nontuberculous ntm
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... /µL Workup • Screen ... consider tissue biopsy ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... (diagnostic for ... Immunohistochemical studies (to differentiate ... #diagnosis #classification ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B lineage ... lineage ALL Symptoms ... , weight loss, abdominal ... #Hematology #Oncology ... #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... lineages—erythrocytic ... with single-lineage ... blood count with differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... lymphoma • Evans ... SLE • Kidney biopsy ... : • Chronic B-cell
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Advanced HIV (CD4 cell ... Hematologic malignancy ... enzymes, diarrhea, abdominal ... washings, Lung biopsy ... NTM #Infections #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... changes (POEMS syndrome ... gastric tumors • Hematology ... #diagnosis #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • Biopsy: Solitary ... Evaluation? ... • Non-Hodgkin Lymphoma ... #Workup #Hematology
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