15 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
is of B-cell lineage ... extramedullary disease ... - infiltrates (anemia ... -> Invade Skin: ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
renal failure/uremia ... Hyperthyroidism CBC ... • Lymphoma • Leukemia ... Pruritus #primary #secondary ... #generalized #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... Diagnosis #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #oncology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Hyperthyroidism CBC ... • Lymphoma • Leukemia ... #Pruritus #secondary ... #generalized #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... Tissue damage • Leukemia ... • Autoimmune diseases ... #differential # ... #CBC #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... Myeloproliferative Disease ... Syndromes #diagnosis #hematology ... #oncology