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diagnosis management oncology differential algorithm anemia aplastic blood cholangitis cirrhosis essential et gap globulin leukemia mds myelodysplasia myelodysplastic normal physiologic
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... intralobular bile ducts causes ... Examination: • Skin ... Hepatosplenomegaly • Spider ... diagnosis #workup #hepatology
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm Face • Melasma Abdomen • Linea Nigra Hormone induced
Physiologic Skin ... Melasma Abdomen • Linea ... Palmar erythema • Spider ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... Detect a spike ... differential #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B lineage ... ALL is of B-cell lineage ... count ↑ PLT • ↑ PBS ... CLL -> Invade Skin ... #Leukemia #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Anemia #oncology #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... infections with skin ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... hematopoiesis cell lineages—erythrocytic ... syndromes with single-lineage ... Syndromes #diagnosis #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... Diagnosis: On the CBC ... megakaryocyte lineage ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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