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management differential signs symptoms activation arthritis cryofibrinogenemia dyspnea gap gca giantcell globulin macrophage mas mds myelodysplasia myelodysplastic oncology protein proteingap
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
HTN - Vasculitis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia • ... #causes #pulmonary
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Hematological: Anemia ... Signs #Symptoms #diagnosis ... #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hematopoiesis cell lineages—erythrocytic ... factor (GCSF) treatments ... with single-lineage ... marrow studies Treatment ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... = vasculitis vs ... systemic complaints- anemia ... Treatment of GCA ... them, but urgent rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... to medium-sized arteries ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... Arthralgia and Arthritis ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... #Rheumatology #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... (RA, Temporal arteritis ... ovarian tumors, lung ... gastric tumors • Hematology ... #hematology
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