12 results
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... Pulmonary edema, Shock ... #Toxicology #diagnosis ... #management #Treatment
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
Abdominal pain, nausea ... deterioration Shock ... and cardiogenic shock ... #Toxicology #Diagnosis ... #Management #Ferrous
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... cycle found in the liver ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis ... #Management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
glucose by the liver ... contribution of liver ... ->treatments include ... mellitus/DKA - Liver ... gluconeogenesis Liver
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
GAS in 30% of cases ... 50% in nec fasc Diagnostic ... (2+): kidneys, liver ... necrosis STSS Treatment ... #management #diagnosis
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Renal: metabolic acidosis ... AI, thyroid dz liver ... Classification #diagnosis ... #management #Overview ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Renal: metabolic acidosis ... AI, thyroid dz liver ... Classification #diagnosis ... #management #Overview ... #differential #causes
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... metabolized in the liver ... Clozapine is known to cause ... #Toxicity #Diagnosis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... heart failure, liver ... heart failure, liver ... heart failure, liver ... heart failure, liver
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (16%) • Shock ... DIC • Severe Liver ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology