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differential signs hepatology insufficiency management phosphatase primary addisons cushings elevation hyophosphatasia hypercortisolism hyperthyroidism low nephrology rhabdomyolysis rheumatology secondary syndrome thyroid
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Intestine - Other causes ... Pregnancy - Renal ... symptoms - Pain
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... mineralization Symptoms ... : - Renal failure ... Phosphatase: • Other causes
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
/vomiting • Abdominal ... pain • Back pain ... Serum DHEAS Diagnosis ... #endocrinology ... #diagnosis #signs
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
ketoconazole, etomidate) Symptoms ... ) w/ anorexia, abdominal ... pain w/ N/V (60 ... , Muscle/joint pain ... #Management #Endocrinology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... : - Muscle pain ... Tachycardia - N/V - Abdominal ... pain Labs: ... of underlying disease
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Anterior neck pain ... fibrillation/flutter • Abdominal ... hyperthyroidism #causes ... #endocrinology ... #signs #symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Hypercortisolism - Diagnosis ... classically purple abdominal ... the abdomen for adrenal ... #signs #symptoms ... #endocrinology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... pain • HTN • ... • Progressive symptoms ... tract, and often causes ... pain and GN Anti-GBM
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