Lymphocyte disease diagnosis classification types causes rheumatology pathophysiology differential cardiology biliary syndrome hematology management lupus vasculitis algorithm

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Cryoglobulinemia Summary

Cryoglobulins:
• Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below

• They can cause ... • Autoimmune diseases ... (e.g. systemic lupus ... #types #classification ... #rheumatology #

Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):

causes differentiated ... Post-strep GN, Lupus ... #differential # ... diagnosis #algorithm ... #rheumatology

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

tract, and often causes ... such as systemic lupus ... differential #diagnosis ... #rheumatology # ... classification

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Classification: ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... • Type-I Interferonopathies ... #Rheumatology

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

glands: • Focal lymphocytic ... hepatitis, primary biliary ... Nephrogenic DI Hematologic ... #Rheumatology # ... Diagnosis #Management

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