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diagnosis leukemia chronic lymphocytic reactions classification cold hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology mds myelodysplasia myelodysplastic syndromes transfusion transfusions variable
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Hepatomegaly • Skin ... can indicate disease ... aplasia • ITP ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... lymphoma (SLL) ... -> Invade Skin: ... #Hematology #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
malignancy (CLL ... malignancies -> CLL ... significance (MGUS), CLL ... #disease #hemolytic ... #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... Transformation to large cell ... lymphoma (Richter ... uw_IMresidency #CLL ... #hematology #hemeonc
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... genes and gene products ... Workup: • Full ... classification #hematology ... #oncology #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... just beneath the skin ... • Anemia • Aplastic ... Syndromes #diagnosis #hematology ... #oncology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... due to marrow aplasia ... Blood products contain ... infections with skin ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
due to marrow aplasia ... Blood products contain ... infections with skin ... #diagnosis #management ... #hematology #reactions
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