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leukemia chronic cll lymphocytic aplastic classification cvid differential gap globulin hemeonc hodgkins immunodeficiency immunology lymphoma mds myelodysplasia myelodysplastic plasmacytoma protein
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... Granulomatous lymphocytic ... #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... (NSHL) - (most common ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Most common cytopenia ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... number of CD34+ cells ... #oncology #hematology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gastric tumors • Hematology ... anemia • Other ... Comment on type ... #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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