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leukemia chronic agglutinin causes classification cold common cvid extravascular hemeonc hodgkins immunodeficiency immunology key lymphoma monoclonal morphology paraproteinemias variable
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) (e.g. lupus, CLL ... #Hemolytic #Intravascular ... #diagnosis #hematology ... #anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Lymphocytes ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... marrow failure with anemia ... #hematology #hemeonc ... #diagnosis #management
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... #key #diagnosis ... #differential # ... hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... - infiltrates (anemia ... (Chronic Lymphocytic ... #Leukemia #Hematology ... #Oncology #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... Diagnosis: • hemolytic ... anemia • Cold ... #hemolytic #anemia ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Granulomatous lymphocytic ... and autoimmune hemolytic ... anemia) • Systemic ... #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... classification #hematology ... #oncology #management
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