13 results
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... due to high ACTH stimulating ... with cosyntropin stimulation ... #Cosyntropin #Stimulation ... #StimTest #Endocrinology
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... - Cosyntropin Stimulation ... BCM_InternalMed #Adrenal ... #Insufficiency ... #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... hormone (ACTH) stimulation ... insufficiency ... insufficiency ... Diagnosis #Algorithm #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... ) Test 2: ACTH Stimulation ... BCM_InternalMed #Adrenal ... #Insufficiency ... Diagnosis #Algorithm #endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: ... • ACTH stimulation ... production • CRH stimulation ... • ACTH stimulation ... diagnosis #testing #endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary Adrenal ... Insufficiency - ... stimulation, thus ... #Insufficiency ... Pathophysiology #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... indicates normal adrenal ... #Insufficiency ... Algorithm #ACTH #Stimulation ... #Test #Endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - ... Test: Cosyntropin Stimulation ... #Insufficiency ... Diagnosis #ACTH #Stimulation ... #Endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's ... Insufficiency: ... Hypoparathyroidism - Type 1 diabetes ... present - ACTH stimulation ... addisons #disease #endocrinology
Etiologies of Hypoaldosteronism

Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone)
 - Diabetic Nephropathy 
 - NSAIDs
Non-Hyporeninemic Hypoaldosteronism (Normal
Aldosterone) - Diabetic ... heparin - Primary adrenal ... insufficiency ... #Aldosterone #Comparison