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differential rheumatology hemophagocytic hlh hodgkins iris lymphohistiocytosis lymphoma myelitis neurology oncology reconstitution summary syndrome transverse treatment vasculitides vasculitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... production of pro-inflammatory ... salmonella, ...), Parasites ... #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... a decrease in HIV ... osteomyelitis, cutaneous abscesses ... leukoencephalopathy (PML ... #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Erythema nodosum • Immune ... ingestion • B symptoms ... #hematology #oncology ... #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... Pleocytosis: Mild lymphocytic ... simplex virus, HIV ... #management #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Necrotizing, pauci-immune ... Syndrome: - Ocular inflammatory ... to exclude are infections ... Presentation - Systemic Symptoms ... classification
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