24 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... features in most cases ... leukemia #APL #APML #Pathology ... #Hematology #Clinical
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... dz difficult to see ... Osteomyelitis / Septic Arthritis ... Hematogenous spread as ... #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
syndrome, rheumatoid arthritis ... life-threatening Differential ... /Cranial nerve pathology ... Generalized fatigue - ALS ... #neurology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... , but they can also ... reticularis Differential ... • Giant cell arteritis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... Medium and large also ... Behcet disease) Differential ... Syndrome #diagnosis #management
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Bacterial Meningitis - Differential ... Adenovirus, • Lymphocytic ... • Common clinical ... /l is regarded as ... #diagnosis #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... affects the skin, neurologic ... elevated protein, lymphocytic ... tract, and often causes ... aneurysms can also
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... very remarkable w/differential ... pain that worsens as ... Symptoms #Diagnosis #Management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... - Causes progressive ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... scans and can also ... classification #hematology ... #oncology #management