8 results
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... Signs/Symptoms/Complications ... non-arousable, decr urine ... pathophysiology #genetics #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Pathogenesis and Clinical ... out of cells may cause ... renal function/urine ... Signs/Symptoms/Complications ... pathophysiology #endocrinology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... cellular function Clinical ... - Causes progressive ... Lateral #Sclerosis #neurology ... #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Dermatomyositis Clinical ... Weakness - Dark urine ... #nephrology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Generalized fatigue - ALS ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management ... #neurology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Diagnosis and Clinical ... same precursor as ... ↑ 24-hour urine ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... status and low urine ... Signs of congestion ... the determined cause ... differential #algorithm #management
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
• Common clinical ... Acute meningeal signs ... established by CSF or urine ... /l is regarded as ... differential #diagnosis #neurology