23 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... #differential # ... pathophysiology #pharmacology ... #potassium #medications
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Normotensive: • UCl ... Post-hypercapnia • UCl ... #Differential # ... Diagnosis #Algorithm #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... - Differential ... • Metabolic acidosis ... blockers - MCW ... Nephrology @MCW_Nephrology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Myeloid Leukemia (CML ... • Diabetic acidosis ... Sarcoidosis • Hypercalcemia ... Hyperuricemia #Differential
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Hypokalemia ... Hyperkalemia ... ACE-Is and ARBs ... #differential # ... diagnosis #causes #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... barrtin (recruits Cl ... renal tubular acidosis ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • NSAIDs • ACE ... - Metabolic acidosis ... Medications 2. ... potassium #high #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Redistribution: Acidosis ... STOP offending medications ... Ca-gluconate or 1g CaCl ... #potassium #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • NSAIDs • ACE ... - Metabolic acidosis ... Medications 2. ... potassium #high #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Chloride Algorithm Cl ... Kidney loss of Cl ... alkalosis • Loss of Cl ... Cystic fibrosis Cl ... #differential #