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diagnosis lupus treatment erythematosus renal systemic differential nephritis syndrome classes diuretics hematology aki algorithm ana antibody antinuclear behcet causes cerebritis
Renal Involvement in Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal #diseases #SLE ... Erythematosus #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels ... #lupus #management
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus #Nephritis #SLE ... #Classification ... differential #diagnosis #management ... #nephrology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... #rheumatology # ... nephrology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... body-like: - Neurologic ... differential #diagnosis #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Mean eGFR - 39.5 mL ... /min • <60 mL/ ... Cryoglobulinemia #Vasculitis #Management ... #Rheumatology # ... Cryoglobulinemic #Nephrology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... least 2 joints • Neurologic ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Erythematosus #SLE ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Migraine - Preventative Treatments • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
Beta-blockers, ACE ... Preventative #Treatment #management ... prophylaxis #prevention #pharmacology ... #neurology
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
increase of 44 mol ... Vancomycin #AKI #pharmacology ... toxicology #diagnosis #management ... #nephrology
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