16 results
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... microcytic anemia (MCV ... normocytic anemia (MCV ... macrocytic anemia (MCV ... /mean MCV) × 100
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... test, ANA (e.g., SLE ... changes), high MCV ... ITP, unexplained pancytopenia ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss ... Reticulocytes, MCV ... , MCH, MCHC, Serum ... Anemia of Chronic Disease ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... extramedullary disease ... blast cells - Blood ... #Hematology #Oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Normal Blood Smear ... • Liver Disease ... #Causes #Hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(cell) volume (MCV ... in peripheral blood ... High in acute blood ... #Diagnosis #Workup ... #Hematology #Microcytic
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... cells can indicate disease ... Lymphocytosis: Absolute blood ... #diagnosis #workup ... #oncology #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
aseptic meningitis), MCC ... : Arterial (MCC-small ... tears, Ischemia, Leukemia ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... virus (EBV) • Leukemia ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... : SLE+++, Adult-onset ... Still disease, ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology