11 results
diagnosis rheumatology comparison cppd lupus thrombocytopenia workup activation antinxp2 antinxp2dm arthritis causes deposition dermatology differential disorders druginduced erythematosus gout hemophagocytic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , dermatomyositis ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... thiazidic, PPI, ACE, calcium-b ... Manifestations: Malar rash ... : Chronic disease ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
l MD SOAP) - Risks ... PT, aPTT(liver disease ... test, ANA (e.g., SLE ... changes), high MCV ... anemia (vegan,
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... erythematosus [SLE ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... crystals (gout) or calcium ... the presence of anemia ... hyperglobulinemia (3) Rises ... profile (e.g., calcium
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Lymphohistiocytosis #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... - infiltrates (anemia ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... dorsal part of the MCP ... had more severe disease ... #diagnosis #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... joints (shoulders, wrists ... locations: Wrist, MCP ... #Rheumatology # ... diagnosis #management
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
joints (shoulders, wrists ... • Underlying disease ... states Pathophysiology ... precipitates with calcium ... locations: Wrist, MCP
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