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rheumatology dermatology management photo dermatomyositis hodgkins lupus lymphoma sle activation antimda5 antimda5dm antinxp2 antinxp2dm classification cppd cutaneous differential druginduced erythematosus
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... • Clinical features ... Differential Diagnosis ... Malignancies (eg CML ... #oncology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Malignancy (e.g. hematologic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Adult-onset Still disease
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... Petechial or purpuric rash ... 5000 to 10,000 ng/mL ... Activation #Syndrome #Diagnosis
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
. diagnosis? ... self-limited Diagnosis ... is clinical & labs ... larva #migrans #skinRash ... #dermatology #clinical
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... severity of the disease ... #dermatology #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #diagnosis #management
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
diffuse palpable rash ... Diagnosis? ... myxoma, Behcet disease ... Vasculitis #LCV #Hand #skinrash ... #dermatology #clinical
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... locations: Wrist, MCP ... #CPPD #Gout #Comparison ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... classical HL (MCHL ... number of sites of disease ... classification #hematology ... #oncology #management
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