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diagnosis management hemophagocytic hodgkins lymphohistiocytosis lymphoma syndrome activation behcet chronic cll comparison differential erythematosus hemeonc leukemia lupus lymphocytic macrophage mas
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
hypersensitivity syndromes • HLH ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types: Classification ... Lymphomas • Other hematologic ... Malignancies (eg CML ... NonHodgkins #comparison #oncology ... #differential #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... (MCHL) - Lymphocyte ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
chemotherapy for low-risk disease ... • Indications ... for Treatment: ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... aseptic meningitis), MCC ... : Arterial (MCC-small ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelogenous Leukemia (CML ... Myeloproliferative Disease ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology ... #oncology
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