12 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Ferritin >500 ng/mL ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... sIL-2R >2400 Ul/ml ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... 5000 to 10,000 ng/mL ... #Diagnosis #Management ... #Hematology #Rheumatology
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
Syndrome (SSSS) ... upper respiratory infection ... patient’s rash is tender ... #Clinical #Photo ... Peds #Pediatrics #Dermatology
Dorsal Foot Corticosteroid Injection

Uncommon dorsum of foot injection. Try to move fluid in tendon to see
Corticosteroid Injection ... move fluid in tendon ... #clinical #video ... procedure #msk #orthopedics ... #sports #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... association • M > F Clinical ... (Clinical Dx). ... #diagnosis #management ... signs #symptoms #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... (MCHL) - Lymphocyte ... classification #hematology ... #oncology #management
Greater Trochanteric Bursa Injection 

Usually roll patient on side, find the most tender spot, approximately an
find the most tender ... Deeper injection ... #clinical #video ... #procedure #rheumatology ... #sports #msk #orthopedics
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... Idiopathic • Infections ... Anemia #oncology #hematology ... #diagnosis #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... , hair growth, skin ... tags, skin thickening ... Beckwith Wiedemann syndrome ... levels to <1ng/mL