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rheumatology dermatology syndrome antimda5 antimda5dm antinxp2 antinxp2dm classification cryoglobulinemia differential erythematosus hodgkins involvement leukemia lupus lymphoma mds monoclonal myelodysplasia myelodysplastic
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
• Absence of skin ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... #Vasculitis #Management ... #Rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... involvement CML ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
dorsal part of the MCP ... ulcerations • Skin ... CD4+ and CD8+ T cell ... 50% of cases • Skin ... dermatology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... , breast CA - Hematologic ... multiforme - Dermatomyositis ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
have typical DM skin ... dorsal part of the MCP ... ulcerations • Skin ... : • ILD was diagnosed ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Still disease, dermatomyositis ... Seizures • Strokes Skin ... La, anti-Jo-1, SCL
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... amyloidosis, PAH Skin ... Nephrogenic DI Hematologic ... Vasculitis: • 7%, Cryoglobulinemia ... #Diagnosis #Management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... just beneath the skin ... Myelogenous Leukemia (CML ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... classical HL (MCHL ... lymph node biopsy (diagnostic ... classification #hematology ... #oncology #management
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