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diagnosis rheumatology differential syndrome allergy antinxp2 antinxp2dm behcet classification dermatomyositis hodgkins immunology leukemia lymphoma mds monoclonal myelodysplasia myelodysplastic paraproteinemias signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
palpable purpura, Pathergy ... response to local skin ... lesions • Positive pathergy ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... Skin manifestations ... #Treatment #management ... #pharmacology # ... rheumatology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
following: • Behcet ... Disease • Pyoderma ... myeloid leukemia (CML ... allergy #immunology #dermatology ... #skin
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Overview: ALL, CML ... extramedullary disease ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
classical HL (MCHL ... number of sites of disease ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Myelogenous Leukemia (CML ... Myeloproliferative Disease ... Syndromes #diagnosis #hematology ... #oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
have typical DM skin ... dorsal part of the MCP ... had more severe disease ... Dermatomyositis #diagnosis #management ... dermatology
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