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diagnosis rheumatology leukemia anemia behcet chronic cll disease erythematosus lupus lymphocytic mds myelodysplasia myelodysplastic polychondritis relapsing signs sjogrens syndromes systemic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... • Improve the symptoms ... #Anemia #oncology ... #hematology #diagnosis ... #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Hepatomegaly • Skin ... Pure red cell aplasia ... diagnosis #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms ... La, anti-Jo-1, SCL
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... just beneath the skin ... Causes • Anemia • Aplastic ... #diagnosis #hematology ... #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... overlaps with RA, SLE ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... Diagnosis #Management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
of idiopathic MCD ... erythematosus (SLE ... and the systemic symptoms ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... • Inner ear • Skin ... cases such as: • SLE ... #diagnosis #management
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