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hematology differential aplastic b12 cardiology chf chronic classification clinical cobalamin criticalcare cytokine deficiency foamed heartfailure hhv8 hodgkins ibd icu inflammatory
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Algorithm Endocrine ... Hematologic • Anemia ... Myasthenia Gravis Pharmacologic ... #Algorithm #causes
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Algorithm • 40- ... , Anemia • Prevalence ... Crohn's > UC Anemia ... /other causes • ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Presentation: • Fever • Fatigue ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Symptoms: • Fatigue ... - infiltrates (anemia ... Leukemia #Hematology #Oncology ... #Diagnosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... slowing, neuropathy, fatigue ... level (< 200 pg/mL ... consider other diagnosis ... #management #nutrition
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Symptoms: • Fatigue ... skin that are caused ... Myelogenous Leukemia (CML ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... classical HL (MCHL ... classification #hematology #oncology ... #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
simply a clinical diagnosis ... cool extremities, fatigue ... the determined cause ... #algorithm #management ... icu #clinical #pharmacology
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KICS) Working Case ... Symptoms: Fatigue ... abnormalities: Anemia ... Syndrome #Kaposi #diagnosis ... #management #hhv8
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