26 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Diuretic Electrolyte ... Excretion Effects Diuresis ... +, Mg2+, Ca2+, Cl ... electrolytes #effects #pharmacology ... #comparison #table
Pharmacologic Treatments of Chronic Hypertension in Pregnancy
Central alpha-agonists
 - Methyldopa
 - Clonidine
Combined alpha- and beta-blocker
 -
Pharmacologic Treatments ... Hydralazine - Diuretics ... Pregnancy #Management #Treatment ... #Pharmacology # ... HTN #Table #Drugs
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... #medications #druginduced
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... Spironolactone MCW ... MCW_Nephrology #diuretics ... #pharmacology # ... halflife #comparison #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Inhibitors of Na+K+2Cl ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology ... #Medications #Table
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
IL-2 therapy, Diuretics ... Membranous GN, MCD ... @kdjhaveri #DrugInduced ... #KidneyInjury #differential
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... (0.5 - 0.8 ng/mL ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Kat_Watson #DrugInduced ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
acid and most diuretics ... filtered Na+/K+/Cl ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... : No • Treatment ... : Supportive + diuresis ... diagnosis #comparison #table