68 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
syndrome Anti-Scl ... polyangiitis U1-RNP antibody ... Endomyseal antibody ... #diagnosis #table ... #rheumatology #
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Warm Antibody Autoimmune ... Hemolytic Anemia 1) DIAGNOSE ... • Blood smear: Differential ... #management #treatment ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies #diagnosis ... #rheumatology # ... diseases
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Diagnosis Congenital ... Diseases: • GATA2 ... hemoglobinuria • Antibody-mediated ... #Diagnosis #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
) - Differential ... Diagnosis Algorithm ... Classification #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Arthritis Summary MCP ... PIP Involvement, Spares ... Scleritis, Heart Disease ... Arthritis #RA #diagnosis ... #rheumatology #
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... Diagnosis Framework ... Non-megaloblastic: Liver disease ... #Algorithm #Differential ... #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm ... Anemia of Chronic Disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... chronic kidney disease ... #differential # ... diagnosis #causes ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... Diaqnoses: • ... #diagnosis #management ... #treatment #rheumatology