13 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... hydration - Hyperkalemia ... diagnosis #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... : • Triad of symptoms ... urine • Other symptoms ... urine output: 200 ml ... #nephrology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... Responsive to Treatment ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
conjunction with symptoms ... diagnosis and treatment ... consistent with MS ... #neurology #noninflammatory ... #differential #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... CNS symptoms (headache ... Behcet disease) Differential ... Arthritis, AS Treatment ... #rheumatology #
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) hypokalemic ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... diagnosis #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... epilepticus Treatment
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
lumbar spine • MCC ... spine L1-L5 Symptoms ... axial T1 and T2 Treatment ... #differential # ... diagnosis #causes #neurology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Then, ask 3 questions ... approach to the differential ... demyelination syndrome ... in 100 mL boluses ... #management #nephrology