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diagnosis hematology differential agglutinin anemia carpal cold disease fracture gap globulin hemolytic management monoclonal msk oncology orthopedics paraproteinemias protein proteingap
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • MGCS • MGRS ... Dermato-neuro syndrome) MGRS ... WAIHA • CAD • PCH ... Paraproteinemias #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... - Mycoplasma, EBV ... significance (MGUS ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Scaphoid Fractures The scaphoid is the most commonly fractured carpal bone. Remember, if a fracture is suspected
Thumb spica • Ortho ... follow-up with PCP ... MH/CCF/CWRU EM
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gammopathy Include: • MGUS ... acute HIV, HBV, EBV ... lung cancers, HCC ... gastric tumors • Hematology ... differential #diagnosis #hematology
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