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management pharmacology criticalcare differential icu psychiatry syndrome adverseeffects altered ams antipsychotic antipsychotics clozapine encephalopathy firstgeneration hcq hemophagocytic hlh hydroxychloroquine hypertension
Delirium in the ICU Defining delirium Types of delirium Consequences of delirium Reversible causes of delirium Drug-induced delirium Non-pharmacologic management of delirium Pharmacologic
ICU Defining ... causes of delirium ... Drug-induced delirium ... #Delirium #pharmacology ... #criticalcare #diagnosis
Neurological Side Effects of Antipsychotic Drugs Acute dystonia - Spasm of muscles of tongue, face, neck, back
Antiparkinsonian agents are diagnostic ... not anxiety or "agitation ... months or years of treatment ... #Medications #SideEffects ... #pharmacology #
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Seizures/NCSE • Delirium ... /agitation • CNS ... Drug (+): ... inhibitors Drug ... #causes
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
it should not cause ... A dissociative drug ... , it causes amnesia ... No pharmacologic ... #diagnosis #management
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
antirheumatic drug ... prophylaxis and treatment ... QTc prolonging drugs ... Hydroxychloroquine #HCQ #Pharmacology ... #SideEffects #AdverseEffects
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
immune deficiency, Drugs ... , Unknown cause ... Treatment: • Etiological ... of emergency, ICU ... #management #treatment
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
, and/or limbs caused ... irreversible • Drug ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology # ... diagnosis #psychiatry
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... antipsychotic drugs ... Clozapine is known to cause ... Toxicology #Toxicity #Diagnosis ... #Pharmacology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
both • Rule out drug-resistant ... superinfection, drug ... cutaneous abscesses, cavitation ... : • Drug reaction ... active infection/drug
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
ingestion and most cases ... weight loss agents, drugs ... pressured speech, delirium ... make a clinical diagnosis ... Pathophysiology #Psychiatry #Diagnosis
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