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diagnosis differential hematology causes nephrology pulmonary vasculitis atlas blood classification erythematosus gap globulin hypertension indications key lupus management monoclonal morphology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
: 3 or more RBC/ ... basement membrane disease ... syndrome: • ... of glomerular disease ... #nephrology #renal
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Lead poisoning • Macrocytic ... Myelodysplastic syndrome ... • Burr cells - Renal ... #differential #hematology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... Dyspnea, Fever, Hematuria ... proteinuria, dysmorphic RBCs ... #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... , proteinuria, hematuria ... Inflammatory eye disease ... mononeuritis multiplex WORKUP ... , RBC casts, low
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... schistocytes, nucleated RBCs ... proteinuria and hematuria ... the presence of renal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... with previously stable ... disease: CKD, acute ... Neurologic disorders ... #Hypertension #Workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
multiplex • Hematuria ... pulmonary and renal ... Lab Tests: • CBC ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... +Organomegaly+↑RBC ... Sneddon-Wilkinson disease ... vascular beds-renal
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... non-nephrotic proteinuria, hematuria ... APLA/LAC: • Renal ... titers > 1:80 • CBC ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mononeuritis multiplex • Hematuria ... pulmonary and renal ... affects the skin, neurologic ... cognitive impairment, neurologic ... Differential #Diagnosis #Rheumatology
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