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rheumatology hemolytic management oncology photo workup activation agglutinin bandemia canimorsus capnocytophaga cbc chronic classification cll cold dermatologic erythematosus eschar gpa
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... inclusions - If infection ... bartonella (oroya fever ... Diagnosis #Algorithm ... #workup #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... lesions (9.4%) • Maculopapular ... reticularis Differential ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
in vasculitic diseases ... inflammation or infection ... petechiae/purpura with fever ... #Diagnosis #Dermatology ... Purpural #Purpuric #Rash
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Clinical Presentation ... anemia • Cold ... younger pts) Differential ... Symptoms: High fevers ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... tachycardia or fever ... #differential # ... #WBC #CBC #hematology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... Dx? ... the key to the diagnosis ... Diseases Fellowship ... #dermatology #clinical
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... weeks without infection ... • Neutropenia, anemia ... workup #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... kidney failure DDX ... SLE], AOSD) • Infection ... with leukopenia, anemia ... #Management #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... weight loss, and fever ... permanent alopecia Differential ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , mucositis • Rash ... vesicles, pustules, maculopapular ... drug exposure or Dx ... #Diagnosis #Rheumatology
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