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blood oncology product reactions stills workup activation adult adultonset chronic classification cll hemolytic hodgkins leukemia lymphocytic lymphoma macrophage mas onset
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... salmon-colored maculopapular ... rash, arthritis ... #AOSD #rheumatology ... #diagnosis #management
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... inclusions - If infection ... bartonella (oroya fever ... Diagnosis #Algorithm ... #workup #hematology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
nonpruritic macular or maculopapular ... Leukocytosis (10,000/microL ... #AOSD #diagnosis ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
kidney failure DDX ... ) • Infection ( ... with leukopenia, anemia ... #Management #Hematology ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... lymphocyte > 5000/microL ... • Neutropenia, anemia ... workup #oncology #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , mucositis • Rash ... vesicles, pustules, maculopapular ... drug exposure or Dx ... #Diagnosis #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
/sx urticaria, maculopapular ... rash, pruritis, ... Infection - Infection ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... /sx urticaria, maculopapular ... rash, pruritis, ... #Transfusions #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Dyspnea • Fever ... number of sites of disease ... classification #hematology ... #oncology #management
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