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management oncology blood lymphoma reactions vasculitis activation chronic cll comparison dermatologic erythematosus gpa granulomatosis leukemia lupus lymphocytic macrophage mas nonhodgkins
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... - Pel-Ebstein fever ... translocation • Types: Classification ... #differential # ... hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
reticularis Differential ... disease • Non-Hodgkin ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Dyspnea • Fever ... genes and gene products ... number of sites of disease ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... cells can indicate disease ... lymphocyte > 5000/microL ... workup #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... kidney failure DDX ... SLE], AOSD) • Infection ... #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... fibromyalgia) • Infections ... cyclophosphamide) • Hodgkin ... #Rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... /sx urticaria, maculopapular ... rash, pruritis, ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
/sx urticaria, maculopapular ... rash, pruritis, ... Infection - Infection ... #Transfusion #diagnosis ... #management #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , mucositis • Rash ... vesicles, pustules, maculopapular ... drug exposure or Dx ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... to exclude are infections ... Vasculitis: • Fevers ... #diagnosis #rheumatology ... #classification
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