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Treatment Approach to Hodgkin's Lymphoma

By Matthew Ho, MD PhD @MatthewHoMD
With Credit: Dr Sunita Nasta and Dr
Treatment Approach to Hodgkin's ... guidelines #Hodgkins ... #Lymphoma #oncology ... #Hematology #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... hematological malignancy ... Lymphoma Workup ... classification #hematology ... #oncology #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hodgkin's Lymphoma ... vs Non-Hodgkin's ... older 50-70 • Malignant ... NonHodgkins #comparison #oncology ... #differential #hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
#DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... PML leukemia, Hodgkin ... Leukemia #diagnosis #workup ... #oncology #hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE in Malignancy ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
chemosensitive malignancy ... Walid Malki, MD, MS ... Syndrome #TLS #oncology ... #management #UricAcid
Checkpoint inhibitors and indications
Anti CTLA-4 antibody:
 • Ipilimumab: Malignant melanoma, Renal cell cancer
Anti-PD-1 antibody:
 • Nivolumab:
• Ipilimumab: Malignant ... • Nivolumab: Malignant ... Gastric cancer, Malignant ... cell lung cancer, Hodgkin ... #indications #oncology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
phenomenon (16%) MSK ... and Arthritis Malignancy ... Risk: • Non-Hodgkins ... Rheumatology #Diagnosis #Management
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
macroglobulinemia • Non-Hodgkin ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology